Nmo Spectrum of Disorders–Clinical, Radiologic and Serologic Profile in Indian Patients

Dr.SREERAMULU DIGUVINTI; Dr. CHENNAKESAVULU DARA

Volume : V, Issue : III, March - 2015

Nmo Spectrum of Disorders–Clinical, Radiologic and Serologic Profile in Indian Patients

Dr. Sreeramulu Diguvinti, Dr. Chennakesavulu Dara

Abstract :

Neuromyelitis optica (also known as Devics disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord. Neuromyelitis optica has a worldwide distribution, poor prognosis, and has long been thought of as a variant of multiple sclerosis; however, clinical, laboratory, immunological, and pathological characteristics that distinguish it from multiple sclerosis are now recognised. The presence of a highly specific serum autoantibody marker (NMO–IgG) further differentiates neuromyelitis optica from multiple sclerosis and has helped to define a neuromyelitis optica spectrum of disorders.We correlate the severity of disease and response to treatment.