Volume : III, Issue : V, May - 2013

Novel Approach of Use of Organic Acids and Salts as a Potent Alternative to Antibiotics

P. G. Umbarkar, Swati. N. Zodpe

Abstract :

Weak acid preservatives appear to share a common mode of action, despite their various chemical structure. These are increasingly potent as antimicrobial agent at more acidic pH value and appears to share a common mode of action. The present study was designed to investigate the antimicrobial activity of some weak acids include acetic acid, maleic acid, citric acid, boric acid and 5–sulphosalicylic acid and some salts such as magnesium sulphate, sodium citrate, sodium carbonate, sodium acetate, potassium permanganate against common pathogenic organisms isolated from various clinical samples. Most frequently encountered organisms are E.coli, P.aeruginosa, K.pneumoniae, S. aureus, E. feacalis. The comparitive study between antibiotics with weak acids and salts was done and the results reveal that acetic acid, maleic acid, sodium carbonate respectively and antibiotic Gentamycin and Imipenem was found to be highly effective in controlling the pathogens whereas the Klebsiella shows the greater resistance towards the antibiotic studied.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

P. G. Umbarkar, Swati. N. Zodpe Novel Approach of Use of Organic Acids and Salts as a Potent Alternative to Antibiotics Indian Journal of Applied Research, Vol.III, Issue.V May 2013

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