OBSERVATIONAL STUDY OF THE EFFECTS OF INJ. ETOMIDATE AS AN INDUCING AGENT IN PATIENTS WITH LOW EJECTION FRACTION FOR NON CARDIAC SURGERIES

Dr. KUSHAL HAJELA; Dr. ANUJA AGRAWAL; Dr. CHINAR PATEL

Volume : VIII, Issue : I, January - 2018

OBSERVATIONAL STUDY OF THE EFFECTS OF INJ. ETOMIDATE AS AN INDUCING AGENT IN PATIENTS WITH LOW EJECTION FRACTION FOR NON CARDIAC SURGERIES

Dr. Kushal Hajela, Dr. Anuja Agrawal, Dr. Chinar Patel

Abstract :

Introduction: Etomidate is a carboxylated imidazole derived nonbarbiturate & the most cardiostable inducing agent. However the adverse effects like myoclonus can be prevented by premedicating with fentanyl.

Method: 50 Patients with ejection fraction 25%–50%, of ASA III and IV posted for non cardiac surgery were premedicated with inj. fentanyl IV. After preoxygenation, induction was done with etomidate 0.3 mg/kg IV over 60 seconds, followed by normal protocol. HR, BP, SpO2, pain on injection & myoclonus were monitored at the time of induction 60, 80, 100 and 120 secs after giving the drug.

Result: There was no significant difference in HR & BP after induction with Etomidate with SD 83.576 ± 14.04, 120.2 ± 9.9 (systolic bp) respectively (p> 0.05) with no pain on injection and insignificant incidence of myoclonus (28 %) (p>0.05)

Conclusion: Etomidate is a Cardioprotective drug with no pain on injection and least complications and side effects.