OBSERVATIONAL STUDY TO COMPARE  INTRAOPERATIVE HAEMODYNAMICS AND RECOVERY PROFILE WITH DESFLURANE AND SEVOFLURANE IN HIGH RISK PATIENTS RECEIVING GENERAL ANAESTHESIA

Dr SUHAS KUMAR  MALL; Dr Chinar Patel; Dr. Rama Upadhyaya

Volume : VI, Issue : IX, September - 2016

OBSERVATIONAL STUDY TO COMPARE INTRAOPERATIVE HAEMODYNAMICS AND RECOVERY PROFILE WITH DESFLURANE AND SEVOFLURANE IN HIGH RISK PATIENTS RECEIVING GENERAL ANAESTHESIA

Dr Suhas Kumar Mall, Dr Chinar Patel, Dr. Rama Upadhyaya

Abstract :

AIMS AND OBJECTIVES: Comparison of desflurane and sevoflurane for intraoperative hemodynamics and postoperative recovery. MATERIAL AND METHODS: Sixty patients classified in ASA III , IV posted for major surgeries lasting for more than two hours randomly assigned to receive sevoflurane or desflurane in general anesthesia. After premedication all patients received inj. fentanyl , induces with inj. propofol and scholine, intubated and maintained on oxygen/nitrogen (50%/50%) with intermittent atracurium. Both group received FGF 4 lit/min for first 10 mins. with desflurane (3–4%) in group I and sevoflurane (2–3%) in group II. After 10 mins. FGF was reduced to 2 lit/min. with inhalational gases adjusted to maintain hemodynamic parameter within 20% of baseline values or according to clinical signs. Inhalational anesthetics were discontinued immediately after closure . Patients were reversed. The times for discontinuation of inhaled anesthetics to spontaneous eye opening , obeying verbal commands , recal of name and orientation of time and place every 2 mins were measured. In post anesthesia care unit aldrete’s score was recorded every 15 mins. till a score of 9 was achieved. Hemodynamics measured every 2 mins prior to skin incision and every 10 mins there after. RESULTS AND SUMMARY: Intraoperative hemodynamics did not differ between the two groups. The time to response to spontaneous eye opening , obeying verbal commands , recal of name and orientation to time and place was shorter after desflurane,however aldrete score was similar. CONCLUSION: Desflurane and sevoflurane produce similar hemodynamic changes but immediate recovery was significantly faster after desflurane.