Volume : III, Issue : VII, July - 2014

Occurrence of Extended Spectrum Beta Lactamase Producing Klebsiella Species in Clinical Samples

Thosar M. G. , V. A. Kamble

Abstract :

Klebsiella species are important and leading in causing nosocomial infections and associated risk factors and being hard to eradicate due to development of multidrug resistant strains that produce extended spectrum beta lactamase (ESBL) enzymes. The aim of this study was to find out the incidence of ESBL producing Klebsiella species from clinical samples. A total of 437 clinical isolates of Klebsiella isolated from 1081 clinical samples and amongst them K. pneumoniae was the commonest (385) followed by K. oxytoca (51), while K. ozanae had only one isolate. All isolates were examined for ESBL production according to CLSI guidelines. The result showed that, 100 isolates of Klebsiella comprising of 66 and 34 from Amravati and Akola districts, respectively were expressed ESBL enzymes. There was no significant difference in prevalence of ESBL producing Klebsiella isolated among various clinical samples collected from Amravati and Akola city. Tests for detection of ESBL producing bacteria should be carried out at all diagnostic centers routinely and use of third generation cephalosporins should be restricted. This can reduce the prevalence of ESBL producing organisms.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Thosar M. G., V. A. Kamble Occurrence of Extended Spectrum Beta Lactamase Producing Klebsiella Species in Clinical Samples Indian Journal of Applied Research, Vol.4, Issue.7 July 2014

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