Ocular Manifestations of Crouzon Syndrome

Dr.Jitendra Kumar; Dr.Naveen Sirohi; Dr.Prayas Vats

Volume : VI, Issue : VI, June - 2016

Ocular Manifestations of Crouzon Syndrome

Dr. Jitendra Kumar, Dr. Naveen Sirohi, Dr. Prayas Vats

Abstract :

 Seven patients with a clinical diagnosis of Crouzon syndrome were assessed before any surgery in the Department of Ophthalmology, Maharani Laxmi Bai Medical College, Jhansi. The ocular features were assessed in these patients. The mean age (in years) in the study group was 13.2 ± 6.7 (range 8 to 27 years). Visual impairment in at least 1 eye occurred in 2 patients (28.6%) and was bilateral in 5 patients (71.4%). The most common cause of visual impairment was amblyopia, which was present in 4 (57%) of patients, followed by optic atrophy in 2 (28.6%). Ametropia occurred in 85.7% of patients; 57% had hypermetropia of ≥ +3 diopters (D) and 28.5% had myopia of ≥ –1.5 D. Strabismus occurred in 57% of patients. Although exposure keratopathy was observed in 2 patients, this complication was well managed and caused no reduction in visual acuity. Ocular protosis, dystopia and hypertelorism were other features seen. Early detection to reduce amblyopia by correction of refractive errors, timely treatment of strabismus, and patching should be a priority. Optic atrophy remains an important cause of visual impairment in such patients.