Organophosphorus Poisoning Cases Requiring Mechanical Ventilation: A Retrospective Study at a Tertiary Hospital

Dr. Kiran.B.R; Dr.Vishwas.G.K; Dr.Dheeraj R Patel Dr.ChiragBabu.P.S

Volume : IV, Issue : X, October - 2014

Organophosphorus Poisoning Cases Requiring Mechanical Ventilation: A Retrospective Study at a Tertiary Hospital

Dr. Kiran. B. R, Dr. Vishwas. G. K, Dr. Dheeraj R Patel Dr. Chiragbabu. P. S

Abstract :

OBJECTIVE: To document the pattern and outcome of organophosphorus (OP) poisoning cases requiring mechanical ventilation in an intensive care unit(ICU) of a Tertiary hospital.DESIGN: Descriptive, retrospective study.METHODS: Medical records of patients of OP poisoning admitted to our intensive care unit(ICU) from January 2011 to December 2011 were reviewed. Diagnosis was confirmed from the historyand clinical findings. Management, complications and outcome were noted. RESULTS:A total 120 patients of OP poisoning admitted in the ICU requiring mechanical ventilation were included in the study.Majority of them i.e. 84(70%) were males.Most of the patients (60.8%)were within the age limit of 30 years. Majority of patients (97.5%) hadsuicidal attempt. In 97.5% patients, ingestion was the route of exposure.Mean ICU stay was5.9 days while 35(29.16%) patients developed secondary complications.Overall mortalityrate was 10%. CONCLUSION:Mortality in OP poisoning is contributed by various factors.Early diagnosis and treatment can significantly improve the outcome.