Volume : X, Issue : III, March - 2020

OSTEOPETROSIS - - A CASE REPORT

Dr Col Om Prakash Singh, Dr Anil Kumar Saroj, Prof R Narain

Abstract :

Osteopetrosis is a very uncommon genetic disorder with characteristic features of increased bone density due to impaired bone resorption by osteoclasts. This leads to increased bone density. It is classified into three forms: Infantile malignant autosomal recessive (AR) Osteopetrosis, intermediate (AR) Osteopetrosis and autosomal dominant (AD) Osteopetrosis. Incidence of infantile malignant AR is 1/2, 00,000 and if untreated has a fatal outcome. The condition is commonly diagnosed in infancy with symptoms of significant hematological abnormalities and bone marrow failure, hepatosplenomegaly, macrocephaly with frontal bossing and bone fractures. As malignant infantile form of Osteopetrosis is very rare, we are reporting a case of Malignant Infantile Osteopetrosis who presented to us with convulsions and a bulging fontanel , anemia and melaena at eight months of age.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

OSTEOPETROSIS - - A CASE REPORT, Dr(Col) Om Prakash Singh, Dr Anil Kumar Saroj, Prof R Narain INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-3 | March-2020

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