Volume : VIII, Issue : IX, September - 2018

Outcomes of renal transplantation with Sibling and Spousal donors; a comparative study

Dr. M. V. K. Hareesh, Dr. R. K. Sharma

Abstract :

Background:Kidney transplantation is the best treatment for End stage renal disease.In the recent years due to increase in number of patients requiring transplantation,there is a shortage of donor organs.Spousal transplantation is emerging as an important way of increasing the donor pool.We present a comparison between Spousal donors(SPD) and sibling donors (SID).

Methods:  202 renal transplant recipients, 101 with sibling donors and 101 with spousal donors matched for age and sex of donor and year of transplantation were compared.Outcomes like graft and patient survival, early and late graft rejections, infections, post–transplant diabetes mellitus,recurrence of diseases were compared.

Results:During follow up there is no significant difference between graft and patient survival between the two groups.Graft rejections were more common among the SPD group but were not statistically significant.Recurrences of diseases were more often observed in SID group.The incidence of infections were similar between two groups.

Conclusion:The outcomes of spousal donor (SPD) and sibling donor(SID) transplant recipients were equivalent.An emotionally motivated spousal donor is the solution for the shortage of donor organs as sibling donations are declining in recent years.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.M.V.K.Hareesh, Dr.R.K.Sharma, Outcomes of renal transplantation with Sibling and Spousal donors; a comparative study, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-9 | September-2018

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