Volume : V, Issue : IV, April - 2015
Paternal Transmission of HIV to the Child of A Seronegative Mother and A Seropositive Father
Alaka Deshpande, Varsha S. Padwal, Atmaram H Bandivdekar
Abstract :
Mother to Child Transmission (MTCT) of HIV is considered during perinatal period. However possible risk
of paternal transmission of HIV is still not understood. A family of HIV infected father, mother and child
was recruited for the study. The mother during first pregnancy was tested HIV seronegative and found seropositive during subsequent pregnancy. The seronegative wife of HIV infected husband delivered first male child who was tested at
the age of four and a half due to pulmonary tuberculosis and found HIV positive. Translated amino acid sequence of
C2–V3 region of env gene of HIV1 in PBMCs of father and son showed 86% homology and that with mother and son
showed 48% homology. These HIV variants showed the sequence identity with Chinese isolates. The study suggests
the paternal transmission of HIV to the son of HIV negative mother and need for parental diagnosis of HIV during perinatal period.
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DOI : 10.36106/ijar
Cite This Article:
Alaka Deshpande, Varsha S. Padwal, Atmaram H Bandivdekar Paternal Transmission of HIV to the Child of A Seronegative Mother and A Seropositive Father Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015
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Alaka Deshpande, Varsha S. Padwal, Atmaram H Bandivdekar Paternal Transmission of HIV to the Child of A Seronegative Mother and A Seropositive Father Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015
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