Volume : V, Issue : IV, April - 2015

Paternal Transmission of HIV to the Child of A Seronegative Mother and A Seropositive Father

Alaka Deshpande, Varsha S. Padwal, Atmaram H Bandivdekar

Abstract :

 Mother to Child Transmission (MTCT) of HIV is considered during perinatal period. However possible risk 

of paternal transmission of HIV is still not understood. A family of HIV infected father, mother and child 
was recruited for the study. The mother during first pregnancy was tested HIV seronegative and found seropositive during subsequent pregnancy. The seronegative wife of HIV infected husband delivered first male child who was tested at 
the age of four and a half due to pulmonary tuberculosis and found HIV positive. Translated amino acid sequence of 
C2–V3 region of env gene of HIV1 in PBMCs of father and son showed 86% homology and that with mother and son 
showed 48% homology. These HIV variants showed the sequence identity with Chinese isolates. The study suggests 
the paternal transmission of HIV to the son of HIV negative mother and need for parental diagnosis of HIV during perinatal period.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Alaka Deshpande, Varsha S. Padwal, Atmaram H Bandivdekar Paternal Transmission of HIV to the Child of A Seronegative Mother and A Seropositive Father Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015


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