PATTERN OF DYSLIPEDEMIA IN ISCHEMIC STROKE PATIENTS �A STUDY FROM GOVERNMENT GENERAL HOSPITAL SIDDHARTHA MEDICAL COLLEGE � VIJAYAWADA � ANDHRA PRADESH

DR.R.SIDDESWARI M.D; DR.T.SIKINDAR MOHAN M.D; DR.SATHYANARAYANA RAO M.D

Volume : VII, Issue : I, January - 2017

PATTERN OF DYSLIPEDEMIA IN ISCHEMIC STROKE PATIENTS �A STUDY FROM GOVERNMENT GENERAL HOSPITAL SIDDHARTHA MEDICAL COLLEGE � VIJAYAWADA � ANDHRA PRADESH

Dr. R. Siddeswari M. D, Dr. T. Sikindar Mohan M. D, Dr. Sathyanarayana Rao M. D

Abstract :

Aim: To study the pattern of dyslipedemia in ischemic stroke patients.

Methods: This a retrospective descriptive study, conducted on 100 patients admitted in Government General Hospital Vijayawada with new onset acute ischemic stroke .A detailed history, physical examination and outcome details of the patients were collected from hospital records. Fasting Lipid profile reports and computed tomography (CT) or magnetic resonance imaging (MRI) ain reports were also obtained from records and studied for pattern of dyslipedemia associated with strokes.

Results: A total of 100 patients were studied of whom males were 68 and females were 32.Patients with age <40 years n=4 age between 40– 60 years n=63 and age >60years n=33 with mean age 58.39 years. In the present study risk factors which were included are hypertension n= 49 diabetes n=21, both diabetics and hypertensive’s n=18 smoking n= 29 ,alcoholism n= 31 and risk factors 2and above n=39 and dyslipidemia (LDL >130;TC>200;HDL<40; Triglycerids >150) mg/dl as per ATP III guidelines was present in n=93 patients . High LDL cholesterol ( >130mg/dl)was found in n= 25 with mean LDL : 104.6 mg/dl, low HDL Cholesterol in n= 83 with mean 34.4 mg/dl, high Total Cholesterol was found in n=19 with a mean 161.73 mg/dl, high Triglycerides n= 28 with a mean 132.1mg/dl. Non HDL (total cholesterol minus HDL) >130 mg/dl was in 39 patients and Total cholesterol and HDL ratio > 4.5 was found in 43 patients.

Conclusion: In the present study among modifiable risk factors for dyslipidemia as per ATP III guidelines was present in 93% of stroke patients. Most of the patients were having low HDL (<40mg/dL) which is a risk factor for stroke fallowed by hypertension and alcoholism. As per the Indian Council of Medical Research (ICMR) surveillance project report prevalence of dyslipidemia (defined as a ratio of total to HDL cholesterol > 4.5) was present in 43 patients. Present study concludes the importance of Therapeutic life style change (TLC), diet and exercise role to cut down dyslipedemia and in reducing the incidence of stroke.