PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 108 women

Reily Ann Ivan; Kuruvilla.P.Chacko; K Natarajaseenivasan; Sarada V; Gomathy Chandran; Prabhu Nagarajan

Volume : VI, Issue : IV, April - 2016

PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 108 women

Reily Ann Ivan, Kuruvilla. P. Chacko, K Natarajaseenivasan, Sarada V, Gomathy Chandran, Prabhu Nagarajan

Abstract :

Human papillomavirus (HPV) infection is recognized today as the main causal factor for cervical cancer cases in the world. Integration of HPV and persistence over time, not merely infection, leads to development of high–grade precancers and cervical cancer. The current study is to evaluate cytological and histological findings with identification of cervical HPV infection using PCR technique. Chronic cervicitis was the major cervical lesion diagnosed in the present study. Maximum HPV positivity was seen in 51 to 60 year age group. In all types of cervical lesions, 31 to 33 percent showed HPV positivity which explains the importance and necessity to vaccinate all girls from 9 to 12 years. Combined with traditional Pap test, detection of cervical HPV –DNA can be very useful in cervical cancer screening programme in India