Volume : V, Issue : V, May - 2015

Platelet indices in the spectrum of Ischemic Heart Disease

Devi Subbarayan, Preethi Ravi

Abstract :

 Background– Ischemic heart disease (IHD) is a leading cause of death in urban area of today’s world. Platelet plays an important role in pathogenesis of atherosclerosis. The mean platelet volume (MPV),  measure of platelet size is a potential marker of platelets reactivity. Studieshave stated that an increase MPV associated with myocardial damage. The current study is undertaken to evaluate the platelet parameters and an attempt  to predict cardiovascular events in Indian population. Materials and methods: A case–control study involving 30 coronary artery disease (CAD), 31 acute coronary syndrome cases (ACS) and 32 controls. Platelet parameters which include  platelet count (PC), MPV, platelet distribution width (PDW) were determined in all groups, compared and statistically  analysed. Results: Significant increase in mean values for MPV, PDW are increased in cases compared to the controls.  Among the cases these parameters are significantly increased in ACS cases compared to stable CAD cases. Results:  our results showed that these simple parameters can be used in routine practice to predict the impending adverse cardiac events.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Devi Subbarayan, Preethi Ravi Platelet indices in the spectrum of Ischemic Heart Disease Indian Journal of Applied Research, Vol.5, Issue : 5 May 2015

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