Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus strain from Clinical Isolates at Gwalior Medical College Hospital

Saroj Kothari; Anubhuti Khare; Vaibhav Misra

Volume : VII, Issue : III, March - 2017

Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus strain from Clinical Isolates at Gwalior Medical College Hospital

Saroj Kothari, Anubhuti Khare, Vaibhav Misra

Abstract :

Present study was undertaken to find the prevalence & antimicrobial sensitivity of Staphylococcus aureus in clinical isolates in tertiary care hospital. Various samples were collected for isolation & antimicrobial susceptibility testing of S.aureus. Out of 5000 samples collected 1684 showed growth in culture media. A total of 255 Staphylococcus were isolated & subjected to antimicrobial susceptibility. High antimicrobial resistance was seen with common antimicrobial agents such as erythromycin, ampicillin, cefixime & ceftazidime+clavulinic acid as 78%, 71%, 71% & 63% respectively. Mean highest sensitivity to linezolid (84%), vancomycin (83%) & doxycycline (82%), whereas mean intermediate antibiotic sensitivity to amikacin (77%), levofloxacin (72%), amoxiclav (64%) & piperacillin (56%) were observed. Present study showed that Staphylococcus aureus (15%) were resistant to commonly used antibiotics & did not show 100% sensitivity to linezolid & vancomycin. Thus, there is urgent need to regulate use of antibiotics in hospital for preventing the spread of antimicrobial resistance.