Prevalence and Antimicrobial Susceptibility Pattern of Blood Isolates in Patients of Septicaemia in Intensive Care Unit: Retrospective study

Dr Kamlesh Kanwar Shekhawat; Dr Vikram Singh Rathore

Volume : VIII, Issue : I, January - 2018

Prevalence and Antimicrobial Susceptibility Pattern of Blood Isolates in Patients of Septicaemia in Intensive Care Unit: Retrospective study

Dr Kamlesh Kanwar Shekhawat, Dr Vikram Singh Rathore

Abstract :

Background: Septicaemia in critically ill patients is life threatening condition and requires rapid antimicrobial treatment. Infections caused by drug–resistant organisms are more likely to increase risk of death in these patients. The aim of the present study was to determine the bacteriological profile of bloodstream infections and their antibiotic susceptibility pattern in an intensive care unit (ICU) of a tertiary care centre in North India.

Materials and Methods: This cross–sectional study was done in a 30–beded adult and 10–beded paediatric Intensive care unit (ICU) from April 2017 to September 2017. Standard bacteriological methods were used for blood collection, bacterial isolation and antimicrobial susceptibility pattern.

Results: Total 241 patients were clinically diagnosed septicaemia during study period of six month and 482 blood samples were analysed, 60 sample yielded growth of 12 type of organism which include 11 type of bacteria and 1 Fungai isolates. Out of total 60 positive samples 46.66% isolates were gram positive bacteria and 46.66% were gram negative and 6.66% were fungi. 118 (48.96%) patients were from MICU followed by 23.65% from PICU. Most common age group was children less than 10 year 29.46% followed by more than 60 Year 16.59% with male preponderance 57.67% and mortality (36.66%) was higher in patients with positive blood culture compare to negative culture (19.66%).

Conclusion: This study provides information on antibiotic sensitivity and resistance of blood isolates found in ICU patients with septicaemia. It will guide the intensivists to formulate the initial empiric antibiotic therapy for the critically ill patients in ICU.