Prevalence and Clinical features of Cryptococcal meningitis in HIV sero–positive patients : Original Reaserch Study in Tertiary Care Hospital.

Dr. Aparna Gaini; Dr. Hema Kumari.E; Dr.B.Srinivasa Rao

Volume : X, Issue : II, February - 2020

Prevalence and Clinical features of Cryptococcal meningitis in HIV sero–positive patients : Original Reaserch Study in Tertiary Care Hospital.

Dr. Aparna Gaini, Dr. Hema Kumari. E, Dr. B. Srinivasa Rao

Abstract :

Aim: To find out the prevalence & clinical features of Cryptococcus neoformans in CSF causing meningitis in HIV seropositive patients and other bacterial pathogens in CSF causing meningitis in HIV seropositive patients. Methods: This Study was undertaken in Government General Hospital , VJA during July 2018 to March 2016.Total 50 HIV sero–positive patients who presented with the clinical features suggestive of meningitis and low CD4 count were screened for cryptococcal meningitis. Results: In present study amongst 50 cases, 4 cases (8%) were positive for Cryptococcus neoformans and 46 cases (92%) were negative for Cryptococcus neoformans. Conclusion: cryptococcal infections should be suspected in all cases of meningitis among HIV seropositive patients as early diagnosis of paramount importance for better management of such patients.