Prevalence of cardiovascular manifestations in patients of Chronic Kidney Disease at a tertiary hospital of Punjab

Dr Gian Chand; Dr Ajay Chhabra; Dr Abhishek Gupta

Volume : VI, Issue : VI, June - 2016

Prevalence of cardiovascular manifestations in patients of Chronic Kidney Disease at a tertiary hospital of Punjab

Dr Gian Chand, Dr Ajay Chhabra, Dr Abhishek Gupta

Abstract :

 Problem statement: Chronic kidney disease (CKD) is becoming a major global health problem. It increases patient mortality and morbidity and puts a major economic strain on the health care system. It is estimated that 1,00,000 new patients of end stage renal disease (ESRD) enter renal replacement programs annually in India. In the absence of any registry in our country these figures were based on estimates. CKD is an important cause of cardiovascular morbidity and mortality. Aims and objectives: Aim was to study the prevalence of cardiovascular dysfunction in patients of chronic kidney disease at a tertiary level hospital of North India. These include ischemic changes and arrhythmias on electrocardiographic evaluation, prevalence and pattern of left ventricular hypertrophy along with systolic and diastolic dysfunction on echocardiography. It was also intended to study the prevalence of pericardial disease in patients with chronic kidney disease. Materials and method: The present study was undertaken to study the pattern of cardiovascular dysfunction in the patients with chronic kidney disease in this part of the country. 100 consecutive patients of either sex attending OPD or admitted at Government Medical College, Amritsar, After informed consent and thorough history taking patients under went certain investigations which included blood urea, serum creatinine, glycosylated haemoglobin, electrocardiogram, 2–dimensional echocardiography with Doppler examination. The results were systematically collected and analysed. Results: Hypertension and dyslipidemia were seen in 78% and 35% patients of CKD. Atrial arrhythmias were found in 12% of patients and Ventricular arrhythmias were found in 21% patients in our study. LVH was found in 63% of our patients. Systolic dysfunction was found in 25% patients whereas diastolic dysfunction was seen in 55% patients. Echocardiographic evidence of pericardial disease was seen in 9% patients.