Prevalence of Rifampicin resistance by CBNAAT in HIV sero–positive patients co–infected with pulmonary tuberculosis, attending tertiary care Centre of Southern part of Rajasthan, Udaipur.

Dr. Manoj Kumar Arya; Dr. Gautam Kumar Bunker

Volume : VII, Issue : VII, July - 2017

Prevalence of Rifampicin resistance by CBNAAT in HIV sero–positive patients co–infected with pulmonary tuberculosis, attending tertiary care Centre of Southern part of Rajasthan, Udaipur.

Dr. Manoj Kumar Arya, Dr. Gautam Kumar Bunker

Abstract :

HIV and MDR–TB have emerged as threats to TB control. The association between MDR–TB and HIV infection has not yet been fully investigated however chance of developing tuberculosis disease is 10–15 times higher than non HIV. Aim: – to know prevalence of MDR–TB in HIV TB co–infected patients. Methods:–HIV positive patients with chest symptoms attended dept. of Pulmonary medicine and Internal Medicine were included. After detail history and examination, chest X–ray and routine investigations were ordered. Sputum were also sent for AFB and CBNAAT. Results: – Out of 58 new PTB case, CBNAAT detect MTB in 35 patients, in which, 34 patients were ‘R’ sensitive, whereas, 1 patient was ‘R’ resistance. The prevalence of ‘R’ resistance in newly treated patient was 2.85% (1/35). Out of 22 previously treated patients, CBNAAT detect MTB in 16 patients, of which 13 were ‘R’ sensitive whereas 3 were ‘R’ resistance. Prevalence of ‘R’ resistance in previously treated patients was 18.75 (3/16). Overall prevalence of ‘R’ resistance in newly treated and previously treated patients was 7.84% (4/51).