Volume : IX, Issue : XII, December - 2019

Prevalence of subclinical hypothyroidism among type 2 diabetes mellitus patients attending the diabetes clinic in a tertiary care medical college and hospital of West Bengal.

Dr Anirban Sinha, Dr. Oishani Mukherjee

Abstract :

Background: It is seen that thyroid disorders and diabetes mellitus mutually influence each other. Diabetes mellitus influences thyroid function at the level of TSH release as well as conversion of T4 to T3 in the peripheral tissues. Numerous epidemiological studies have shown a higher prevalence of subclinical hypothyroidism among type 2 diabetes mellitus patients than in the normal subjects. Hence this study is done to elicit the prevalence of subclinical hypothyroidism among type 2 diabetes mellitus patients of West Bengal which may help in their further treatment. Methods: In this cross–sectional study, 100 consecutive type 2 diabetic patients without any clinical manifestations of thyroid disorders were assessed for hypothyroidism using serum free T4, T3 and TSH levels. They were then compared with 100 healthy individuals chosen as the control. The lipid profile and diabetic profile of the patients was also done. Results: In the above study, prevalence of subclinical hypothyroidism among Type–2 diabetes mellitus patients was found to be 16% showing an association between T2D and thyroid dysfunction. The prevalence is higher in women than men and increases with age (>65years). However, FT4 and TSH levels were not significantly different between the diabetic and control groups. There was also a significant positive correlation between serum cholesterol levels and serum TSH levels. Conclusion: SCH was detected in 16% of type 2 diabetic patients and none had subclinical hyperthyroidism in our study. Elevated TPO antibody levels were present in 81.25% SCH patients. Diabetic retinopathy among SCH patients showed significant association with higher serum TSH levels. Patients with type 2 diabetes mellitus should be routinely screened for SCH to prevent complications and long–term mortality and morbidity.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

PREVALENCE OF SUBCLINICAL HYPOTHYROIDISM AMONG TYPE 2 DIABETES MELLITUS PATIENTS ATTENDING THE DIABETES CLINIC IN A TERTIARY CARE MEDICAL COLLEGE AND HOSPITAL OF WEST BENGAL., Dr Anirban Sinha, Dr. Oishani Mukherjee INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-12 | December-2019

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