IJAR - Indian Journal of Applied Research

Dr. Amrita Chaurasia; Dr. Shalu Mishra; Dr. Vandana Ojha; Dr. Shalini Singh

Volume : X, Issue : IV, April - 2020

PREVALENCE OF THYROID DISORDERS IN PREGNANCY AND ITS-MATERNAL COMPLICATIONS - A PROSPECTIVE STUDY

Dr. Amrita Chaurasia, Dr. Shalu Mishra, Dr. Vandana Ojha, Dr. Shalini Singh

Abstract :

Introduction : Development of thyroid disorders during pregnancy can lead to adverse pregnancy outcomes . Thyroid function tests during pregnancy are also affected by estrogen–mediated increases in the level of thyroxine–binding globulins . It is well documented that maternal thyroid disorders are associated with adverse outcomes in the mother and fetus, including miscarriage, preterm delivery, pre–eclampsia, and placental auption . Decreased availability of maternal thyroid hormone may also impair neurological development of the fetus as several studies have reported decreased IQ in infants born to mothers with either hypothyroidism ,hyperthyroidism . Hence there is a need for universal screening for thyroid dysfunction during pregnancy Aims & Objectves : To study the prevalence of thyroid disorders in pregnancy and its maternal outcome. Materials and Methods: The study is an observational study carried on 200 pregnant females attending antenatal clinics in Department of Obstetrics and Gynaecology of Swaroop Rani Nehru and Kamla Nehru Memorial hospital ,Prayagraj from September 2018 to September 2019. Results: It was observed that the maximum numbers of patients were in 21– 30 years (67%) age group. Euthyroid (87%), overt hyperthyroid (1%), subclinical hyperthyroid (2%),overt hypothyroid (2%), and subclinical hypothyroid (8%) cases were detected. In present study incidence of maternal complications like Preeclampsia,Preterm delivery, Abortion,Auption and Hyperemesis gravidarum was found to be statistically significant in pregnant female with thyroid disorders (p–value=0.04) Conclusion: Present study concludes that there is significant association between thyroid disorders and adverse maternal outcome (p–value=0.04).. TSH is the hallmark in detection of hypothyroid as well hyperthyroid so TSH should be included in the list of routine investigations done in all antenatal women in first trimester