Volume : IX, Issue : III, March - 2019

Procalcitonin: as an early diagnostic marker for neonatal sepsis

Vaishali Kongre, Hemangi Ingale, Renu Bharadwaj

Abstract :

Introduction: Early detection of neonatal sepsis is essential to reduce mortality and morbidity associated with it. Though blood culture is the gold standard for diagnosis it takes long time and can be false negative. So, there is a need of a rapid diagnostic test with good sensitivity and specificity. Aim of the study: To determine the diagnostic performance of serum Procalcitonin (PCT) in neonatal sepsis as compared to C– Reactive protein (CRP) and blood culture. Methods: 50 neonates with clinical signs of sepsis were included in the study. Blood sample was collected from each of them for culture, serum PCT and CRP level estimation. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of PCT and CRP were determined. Results: Out of the 50 neonates, 3 were culture confirmed sepsis. PCT was positive in 28 cases with sensitivity, specificity, PPV and NPV as 100%, 46.8%, 10.7% and 100% respectively. CRP was positive in 20 cases with sensitivity, specificity, PPV, NPV as 100%, 69.7%,35%, and 100% respectively. All the culture confirmed cases were PCT and CRP positive. Conclusion: PCT can be used as an early detection marker in neonatal sepsis along with CRP

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

PROCALCITONIN: AS AN EARLY DIAGNOSTIC MARKER FOR NEONATAL SEPSIS, Vaishali Kongre, Hemangi Ingale, Renu Bharadwaj INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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