Prognostic role of bone marrow biopsy in multiple myeloma- A tertiary center study of 50 patients

Roopal Rathi; Amit Gharia; Tejinder Singh

Volume : IX, Issue : III, March - 2019

Prognostic role of bone marrow biopsy in multiple myeloma- A tertiary center study of 50 patients

Roopal Rathi, Amit Gharia, Tejinder Singh

Abstract :

Multiple Myeloma is a common old age malignancy, with increased monoclonal plasma cells in bone marrow. We studied bone marrow biopsy of 50 such patients for various parameters including tumor load (confirmed by using CD38, CD 138), pattern of involvement, cellularity, differentiation of plasma cells, residual hematopoiesis, and fiosis. Osteolysis, surface resorption and amyloidosis were also noted as rare findings. These prognostic factors are accurately assessable only on biopsy are important in a center where IL–6 and ß2 microglobulin assays are not available.