PROGNOSTICATION OF ISCHEMIC STROKE OUTCOME BASED ON THE GLYCEMIC CONTROL

Dr Sandeep Kumar; Dr YS Sirohi; Dr SP Gorthi; Dr Vikram Asturkar

Volume : VI, Issue : X, October - 2016

PROGNOSTICATION OF ISCHEMIC STROKE OUTCOME BASED ON THE GLYCEMIC CONTROL

Dr Sandeep Kumar, Dr Ys Sirohi, Dr Sp Gorthi, Dr Vikram Asturkar

Abstract :

Diabetes mellitus is a well–recognized risk factor for stroke. Stroke in hyperglycemics is different from stroke in normoglycemic patients from several perspectives. Aims: To compare distinctive patterns between hyperglycaemic and normoglycemic stroke, and to correlate the effect of admission glucose levels on the outcome of both groups. Settings and Design: The present study is prospective case control observational study, carried out at two Hospitals in South Delhi. All cases having acute onset ischemic stroke between Apr 2011 and Apr 2013 and meeting strict inclusion and exclusion criteria were included in the study. Acute stroke was confirmed by physical examination and CT ain to have ischemic stroke. Research question– whether patients of acute ischemic stroke presenting with hyperglycemia at onset will have a different functional outcome as compared to patients with normo–glycemia at the end of 3 months? Results: Fifty patients with ischemic stroke were enrolled (Thirty were hyperglycemics or found to have hyperglycemia at time of admission / at onset of stroke and twenty were normoglycemic patients). Mean admission blood sugar was higher in hyperglycemics than normoglycemic group. Admission hyperglycemia or diabetic patients have worse outcome in the form of more severe disability and dependency at 90 days from the onset of stroke as compare to normoglycemic patients. Conclusions: Stroke in hyperglycemic patients has poor prognosis which emphasizes the need for early diagnosis and treatment of diabetes. Admission hyperglycemia / hyperglycemia at onset of stroke in diabetic patients has severe stroke with the worse outcome on day 90 from onset of ischemic stroke as compared to normoglycemic patients. Knowledge gap is that the relationship between stroke outcome and blood sugar has not been studied on Indian population in the past