Volume : IV, Issue : XI, November - 2014

Protective Effect of Smilax china on Mercuric Chloride Induced Oxidative Stress in Testis

Dr. S. Saravana Kumar, Dr. Christilda Felicia

Abstract :

Smilax china L. is indigenous to China and Japan but it is imported to India and is common in Indian bazaars. It is commonly known as Jin Gang Teng in Chinese, Chobchini in Hindi, and Madhusnuhi in Sanskrit and china root in English. It possesses anti– inflammatory, diuretic, anti–diabetic, anti–psoriatic, digestive properties. Free radicalscavenging and antioxidantenzymepromotingactivities were observed in the extracts of Smilaxchina L. rootMercury(HgCl2) induces various toxic effects in different organs of the body.The present work is to evaluate the beneficial effect of Smilax china on mercuric chloride induced oxidative stress in rat testis.Theantioxidativeindices assayed were superoxideDismutase, catalase and lipidperoxidase. Mercury exposure shows decrease in the levels of antioxidants such as SOD and CAT , increased levels of TBARS. Prophylatic administration of Smilax china (400mg /Kg/ Bw)causes increase in the level of SOD and CAT for animals treated with low dose of Merucry (0.5mg/kg/Bw) and also decrease in the levels of TBARS ( P<0.001) significantly, was noticed. In animals on High dose of Mercury chloride the effect of Smilax china is less when compared to the low dose the drug.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.S.Saravana Kumar Protective Effect of Smilax china on Mercuric Chloride Induced Oxidative Stress in Testis Indian Journal of Applied Research, Vol.4, Issue : 11 November 2014

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