Volume : IX, Issue : VI, June - 2019

QUORUM SENSING AND IN SILICO SYSTEM NETWORK STUDIES IN K. PNEUMONIAE

Dsvgk Kaladhar, Aabha Barman

Abstract :

Klebsiella pneumoniae is a gram–negative bacteria and was an opportunistic pathogen that secrete type 2 signaling molecules leading to quorum sensing. The protein–protein interactions of pelC, rhlR, luxR and lasR has shown relationships and properties with Polysaccharide biosynthesis, Bioluminescence, Acid tolerance, Rhamnolipid biosynthesis, Virulence factor induction, pyocyanin biosynthesis and Biofilm formation. The analysis is conducted based on the interactions and analysis of KEGG and String databases, the mechanism of genes has been initiated as hyid method in the present work. The docking result has shown that oxytetracycline has shown beter activity with pelC, rhlR, luxR and lasR receptors may be active against Biofilm formation by Klebsiella pneumoniae.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

QUORUM SENSING AND IN SILICO SYSTEM NETWORK STUDIES IN K. PNEUMONIAE, DSVGK Kaladhar, Aabha Barman INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-6 | June-2019

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