Volume : I, Issue : XI, August - 2012

Rate Pressure Product In Type 2 Diabetic Cardiac Autonomic Neuropathy

Dr Rishu Segan

Abstract :

Cardiac autonomic neuropathy is linked to unexplained sudden and silent death in type 2 diabetics. Altered cardiovascular haemodynamics or blood flow may be substantially involved in adverse cardiovascular mortality. Case control study was done on age matched (40–60years) type 2 diabetics (n=100) with and without cardiac autonomic neuropathy divided into two groups of 50 each. Rate pressure product, non invasive indicator of myocardial blood flow, was calculated and results analysed using one way ANOVA (SPSS software). A significantly heightened rate pressure product was observed in cardiac autonomic neuropathy patients compared to non neuropathy counterparts (p<0.1). Resting rate pressure product was found to be highest (>12) in neuropathy patients. Our findings suggest that type 2 diabetic cardiac autonomic neuropathy significantly increases resting rate pressure product. This reflects heightened resting myocardial blood flow. It leaves little capacity of the body to increase blood flow further especially at times of need contributing to exaggerated ischemic episodes.  

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr Rishu Segan Rate Pressure Product In Type 2 Diabetic Cardiac Autonomic Neuropathy Indian Journal of Applied Research, Vol.I, Issue.XI August 2012

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