Volume : VII, Issue : VII, July - 2017

RECENT ADVANCES IN CRANIOSYNOSTOSIS AND FUTURE PROSPECTIVE

Mayadhar Barik, Pravash Ranjan Mishra, A. K. Mahapatra

Abstract :

 Objective: Craniosynostosis (CS) is the premature ossification and genetically heterogeneous in conditions. We   aim to focus on recent advances with future prospective on Craniosynostosis.

Material and Methods: We observed (since1990 to till 2017)   through different databases of world literature and add our experience with recent advances and future prospective in Craniosynostosis in both the group (syndromic and non syndromic) and additional anomalies.

Results: The pathologies result from complete loss of gene function, biochemical mechanisms involving haploinsufficiency, dominant gain–of–function and recessive hypomorphic mutation (RHM). X–linked cellular interference process been implicatedfew of the genes involved could predicted based on their expression patterns. Genes play much wider roles in emyonic development or cellular homeostasis (CH). Here we argue that they fit into a limited number of functional modules active at different stages of cranial suture development (CSD).

Conclusion: Recent advances in neurosurgery, neuromonitoring and neurointensive care (NIC) have dramatically improved the outcome in patients affected by surgical lesions of central nervous system (CNS). Most of these techniques were applied first in the adult population; paediatric patients present a set of inherent challenges.Recently their developing and maturing neurological and physiological status, apart from the CS disease process and phenotypic pattern. 

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Mayadhar Barik, Pravash Ranjan Mishra, A. K. Mahapatra, RECENT ADVANCES IN CRANIOSYNOSTOSIS AND FUTURE PROSPECTIVE, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾7 | July‾2017

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