Relationship Between Coronary Risk Factors, Bone Mineral Density and Carotid Circulation Among frail elderly

Moatasem Salah Amer; Tamer Mohammed Farid; Ekramy E. Abd el–rahman; Omar Hussein Omar; RandaAbd el–wahaabMabrouk

Volume : IV, Issue : XII, December - 2014

Relationship Between Coronary Risk Factors, Bone Mineral Density and Carotid Circulation Among frail elderly

Moatasem Salah Amer, Tamer Mohammed Farid, Ekramy E. Abd El Ndash Rahman, Omar Hussein Omar, Randaabd El Ndash Wahaabmabrouk

Abstract :

Background& aim of the work: To study the relation between bone mineral density, coronary risk factors and frailty in elderly and also the changes in carotid intima–media thickness(CIMT) and their relation to other comorbidities in frail elderly. Methods:104 elderly patients, who were assigned to: Group A (52 frail participants) and Group B (52 non–frail participants) diagnosed by Fried’s criteria as applied by Avila–Funes et al., 2008. Assessment of all participants included: History, examination, comprehensive geriatric assessment, measurement of BMD by DEXA scan, measurement of CIMT by carotid ultrasound and laboratory investigations including; low density lipoprotein (LDL), high–density lipoprotein(HDL), total cholesterol, and triglycerides.Results: The frail group had significantly lower levels of HDL, CIMT was significantly higher ,BMD was lower when compared with the control group. Frail cases also had higher ADL & IADL assistance, were more depressed with increasing cognitive impairment and mean number of associated comorbidities. CIMT was positively correlated to age and number of chronic diseases. Conclusion: Frailty is associated with changes in markers like HDL which may suggest its use in identification of frailty. CIMT was positively correlated to age & the number of comorbidities. These findings may support the hypothesis that frailty is associated and overlaps with disability