RELATIONSHIP BETWEEN INTRA–ABDOMINAL FAT AND OVULATION IN OBESE POLYCYSTIC OVARIAN SYNDROME PATIENT: A PROSPECTIVE STUDY IN INDIAN POPULATION

Madhuri Panigrahi; Santosh Kumar Panda

Volume : VII, Issue : XII, December - 2017

RELATIONSHIP BETWEEN INTRA–ABDOMINAL FAT AND OVULATION IN OBESE POLYCYSTIC OVARIAN SYNDROME PATIENT: A PROSPECTIVE STUDY IN INDIAN POPULATION

Madhuri Panigrahi, Santosh Kumar Panda

Abstract :

Obesity and PCOS is one of the major modifiable causes of fertility problems. The aim of our study was to compare the changes in body fat distribution between a group of anovulatory women with PCOS and obesity who resume ovulation (Ov+) to those who remain anovulatory (Ov–) undergoing a lifestyle modification programme.

60 anovulatory women with PCOS underwent a 6 month lifestyle modification programme. Body fat distribution was assessed by anthropometrics, ultrasonography, and multi slice abdominal CT scan at beginning, after 3 months and after 6 months and analysed statistically.

It was found from the study that–: The total group of Ov+ women lost more weight (6.7 versus 2% at 6 months, and abdominal fat(IAF) on CT (18.5 versus 1.04% at 3 months) compared with the total group of Ov– women, At 6 month the difference was 31% in Ov+ compared to 8% in Ov– .

The IAF on USG had reduced in Ov+ from baseline as 5.2% at 3month and as 12.2% at 6 month, in comparison Ov– showed reduction as 1.7% at 3 moth and 3.4% at 6 month.

In Ov+ women, there was a difference in loss of SAF (CT) between baseline and 3 months (7 versus 0 .8% ) compared with Ov– women. At 6 month the difference was 16% versus 3.2%.

SAF (US) had reduced in Ov+ from baseline as 7.7% at 3month and as 13% at 6 month, in comparison Ov– showed reduction as 1.2% at 3 month and 2.4% at 6 month.

It may be concluded that–: In anovulatory women with PCOS and obesity undergoing a lifestyle programme, Ov+ women lose more body weight and abdominal fat than Ov– women. Loss of IAF is more associated with resumption of ovulation