Relationship between serum level of uric acid and out come of elderly patients admitted to geriatric ICU with systemic infection on admission

Dr. Somaia M. Ebeid; Dr. Nahla Fawzy Abou elezz; Dr. Heba Y. Kamel

Volume : V, Issue : XI, November - 2015

Relationship between serum level of uric acid and out come of elderly patients admitted to geriatric ICU with systemic infection on admission

Dr. Somaia M. Ebeid, Dr. Nahla Fawzy Abou Elezz, Dr. Heba Y. Kamel

Abstract :

&lt;p&gt;&amp;lt;p&amp;gt;&amp;amp;nbsp;Background : the debate about the role of serum uric acid as an anti&amp;amp;ndash;oxdant versus being a substance that exert oxiidative stress upon the living cell in vivo which affect the prognosis of different illnesses including infectous diseases is an interesting issue for research. Objective: of the current study was to evaluate the relationship between serum uric acid and prognosis of a group of elderly patients who had solitary or multiple sites of infections upon admission to geriatric ICU (Intensive Care Unit). Methodology : forty four elderly patients , both males and females , sixty years old and above were recruited from the ICU of Geriatric department, Ain Shams university hospital. And they were divided into cases and control groups according to their serum uric acid on admission, they were subjected to history taking included: demographic data, SOFA score, site(s) of infection and prognosis upon discharge. then serum uric acid , serum creatinin and BUN(Blood Urea Nitrogen) were measured within 24 hours of admission Results: among the participants the median serum level of uric acid was 7.235 &amp;amp;plusmn; 2.95 with no statistically significant correlation between it and the socio&amp;amp;ndash;demographic and clinical data of the patients, but there was statistically significant correlation between it and prognosis of the patients while sofa score not. By ANOVA test only serum uric acid and creatinin showed statistically significant correlation with the prognosis while age, gender and serum BUN didn&amp;lsquo;t. Conclusion &amp;amp;amp; Recommendation: uric acid is an important prognostic factor for ICU elderly patients and should be investigated more whether to be routine investigation or not for this group of patients.&amp;lt;/p&amp;gt;&lt;/p&gt;