Relationship of Serum Uric acid with Type II Diabetes Mellitus

Dr.M.Aparna; Dr.K.Amarnath Reddy; Dr.A.Padma Vijayasree; Dr.Blessy Prabhu Priyanka

Volume : VI, Issue : IX, September - 2016

Relationship of Serum Uric acid with Type II Diabetes Mellitus

Dr. M. Aparna, Dr. K. Amarnath Reddy, Dr. A. Padma Vijayasree, Dr. Blessy Prabhu Priyanka

Abstract :

Introduction: Diabetes mellitus is a group of metabolic disease characterized by high blood glucose levels that results from defects in insulin secretion or action or both. Some recent studies had shown that elevated level of uric acid is involved in the pathogenesis of type 2 diabetes, regardless of other characteristics of subjects. Aims and Objectives: Our aim was to investigate the correlation of serum uric acid concentration with Diabetes mellitus. Materials & Methods: One hundred and fifty type 2 diabetes mellitus subjects (male 80, female 70) and fifty non–diabetic subjects (25 male, 25 female) were included in the study over 1 year (June 2015 to May 2016). The study was conducted in the Department of Biochemistry, Kurnool Medical College, Kurnool. Uric acid was measured by enzymatic method. Results: The level of uric acid was higher in male and female diabetic subjects (p<0.05 and p<0.001) compared to non–diabetic subjects. Conclusion: Uric acid showed a positive association with fasting blood sugar (FBS), diastolic blood pressure, in case of diabetes subjects. These data strongly suggest that compared to non–diabetic subjects, diabetic subjects have significantly higher uric acid level.