Resistance Patterns to Beta�lactams and Aminoglycosides of Enterobacteria Strains Isolated From Wounds Infections at University Hospital Center of Brazzaville

Rachel MOYEN; Etienne NGUIMBI; Nina  Esther ONTSIRA NGOYI; Gabriel AHOMBO; OBENGUI

Volume : VI, Issue : XII, December - 2016

Resistance Patterns to Beta�lactams and Aminoglycosides of Enterobacteria Strains Isolated From Wounds Infections at University Hospital Center of Brazzaville

Rachel Moyen, Etienne Nguimbi, Nina Esther Ontsira Ngoyi, Gabriel Ahombo, Obengui

Abstract :

Background: In order to contribute to the improvement of antibiotic therapy in hospital medium,, The strains of Enterobacteriaceae isolated of wounds homes hospitalized patients were tested in their sensitivity to beta–lactams and aminoglycosides. Materials and Methods: The pus was inoculated on Hecktöen medium (Biomerieux); different enterobacteria were identified from the cultural characters then using a conventional gallery Leminor. The testes of sensitivity were performed by standard diffusion susceptibility testing on Mueller Hinton agar (Biomerieux). Results: Enterobacteriaceae accounted for 76% of bacteria isolated from wounds; the identification gave the following genres: 23 strains of E. coli (30.26%), 22 strains of Proteus (28.95%), 12 strains of Klebsiella (15.78%), 8 strains of Enterobacter (10.53%), 6 strains of Citrobacter (7.89%), and 5 strains of Providencia (6.57%). The results of antibiotic susceptibility showed high resistance to beta–lactam antibiotics compared with aminoglycosides. These bacteria present in the stem majority the same characteristic phenotypes of inhibition of beta–lactam and aminoglycoside activity Conclusion: Since the beta– lactam antibiotics are the first–line antibiotics, these results show the danger of these multiresistant bacteria that constitute a real problem of public health