Retinal Changes in Melatonin Consuming Patients Using Electroretinography

Farabi Y. Shushtarian S.M. Khatibi S.

Volume : VI, Issue : III, March - 2016

Retinal Changes in Melatonin Consuming Patients Using Electroretinography

Farabi Y. Shushtarian S. M. Khatibi S.

Abstract :

Aim: sleep disturbances is a complication observed in elderly population. Melatonin is a drug to treat these patients. It is reported that this treatment may produces visual problems. The aim of present research is to look for probable retinal changes in melatonin consuming patients using Electroretinographical technique. Methods: thirty patients with different period of melatonin prescription were selected for the purpose of present study. They were classified in four groups according to the period of drug medication. Flash ERG was used as a technique to check the retina of these patients. Latency (m sec) and Voltage (µv) of ERG, b wave were recorded for each patients. The values obtained were compared with the normal population (control) to see for the possible differences between two groups. Results: It is observed that melatonin increases the latency of b wave of ERG, where as it does not effect the amplitude of b wave significantly. Conclusion: It is already reported that increase in latency of ERG, b wave is the result of early deep retinal degeneration, so one can conclude that Melatonin produces deep retinal degeneration which can be diagnosed by measuring the latency of ERG, b wave, which will be discussed in detail in full paper.