RETROSPECTIVE STUDY OF ADULT POPULATION SEPSIS IN ICU PATIENTS IN TERTIARY CARE CENTRE

Volume : VIII, Issue : V, May - 2018

Dr Ashish Tale, Dr Vrushali Bhoite, Dr Shilpa Sule, Dr Khalid Khatib

Background and Aim: Sepsis is a major cause of morbidity and mortality worldwide. To determine the incidence and

outcome of sepsis among adult patients, a retrospective study was conducted in Intensive care unit (MICU, ICCU, SICU)

in a tertiary care center from July2017 to December 2017. Age,gender,requirement of Mechanical ventilation and Hemodialysis , SOFA score

and sorce of infection was compared among survived and non–survived sepsis patient.

Materials and methods: all 648 patients admitted in ICU over six months were included in study. Patient‘s data was extracted from inpatient

record charts and investigation reports. Variables measured were patient‘s demographic data, incidence of sepsis, mean SOFA Score on Day 1

and Day 3, source of sepsis or infection site, whether patient required mechanical ventilation and /or hemodialysis and outcome in the form of

survival.

Results: There were 648 admissions to ICU during study period with 100 cases of sepsis(15.43%). Mean age of sepsis patient was 64.5 years.

Maximum patients were from age group 41–50. Male to female ratio was 1.6:1. Predominant source of infection was respiratory tract infection.

Mean SOFA score on Day1 was 9.03 and on Day 3 was 10.02.Out of 100 patients of sepsis 55 patients‘ required mechanical ventilation and 37

patients required hemodialysis. ICU mortality was 58%.There was significant difference (<0.001) between requirement of ventilation among

survived and non–survived sepsis patients. SOFA score was significantly high in non–survived patients on Day 1 and 3

Conclusion: sepsis is common in ICU. Mortality rate is high in this group.