IJAR - Indian Journal of Applied Research

Manjeet Singh; Shalini Sharma; Jyoti Kumar; Mukesh Kumar

Volume : VIII, Issue : III, March - 2018

Revisualising Event Related Potential P300 through prism of total number of stimulations

Manjeet Singh, Shalini Sharma, Jyoti Kumar, Mukesh Kumar

Abstract :

Background: Event Related Potential (ERP) P300 is a neurophysiological response that reflects the status of cognition and memory related functions. P300 latency increases with cognitive decline. Sometimes disturbances appear in the lag phase of recording due to movements of head or loosening of electrodes over scalp. So it was decided to investigate that if effect of less number of stimuli is not significantly different from total number of stimuli, we can report the result of earlier one in case of any error appeå later during the procedure.

Aim & Objective: To study the effect of total number of stimulations on ERP P300.

Material & Methods: This cross sectional study included 30 subjects of age > 18 years of either sex. ERP P300 latency was recorded as per standard procedure at four levels categorized as groups A,B,C and D on the basis of total number of stimulations i.e. during 140–160 stimulation [A], 190–210 stimulation [B], 240–260 stimulation [C] and automatic at the end i.e. 300 stimulations [D]. All the data so obtained of same individual at four levels were compared and analyzed statistically.

Results: There were no significant differences among groups in relation to P300 latency.

Conclusion: Minimally exposure of 150 tones in total or 30 rare tones is required to get stabilized ERP P300 latency so the recording beyond this at any range of stimulations can be considered as final recording if any error occurs later on during the process.