ROLE OF COMPUTED TOMOGRAPHY PERFUSION IN CHARACTERISATION OF SOLITARY RENAL LESIONS.

Dr SWARNALAKSHMI S; Dr.K. SHIVASHANKAR; Dr. D. RAMESH

Volume : IX, Issue : III, March - 2019

ROLE OF COMPUTED TOMOGRAPHY PERFUSION IN CHARACTERISATION OF SOLITARY RENAL LESIONS.

Dr Swarnalakshmi S, Dr. K. Shivashankar, Dr. D. Ramesh

Abstract :

AIM: To study the differences among the CT perfusion parameters (BF – Blood Flow, BV – Blood Volume, PMB – Permeability) obtained from various renal lesions and to correlate with the histopathological diagnosis, and grading. METHODOLOGY: It was a prospective study conducted in Barnard Institute of Radiology with a sample size of 40. Patients referred from Urology department with renal lesion diagnosed on US / Conventional CT, who are willing for CT perfusion were included in this study. All CT perfusion studies were done using 16 SLICE CT scanner (SOMATOM EMOTION, SIEMENS HEALTHINEERS). First, an unenhanced scan was obtained covering entire kidneys, following which, perfusion study was done. After image analysis and post processing, quantitative perfusion parameters were obtained. These findings were correlated with histopathological reports. RESULTS: All three parameters (BF, BV, PMB) were significantly lower (P<0.01) in RCC than oncocytomas. Permeability was better in differentiating RCC and oncocytoma with 93.8% sensitivity and 100% specificity. Also, BF, BV, PMB were significantly higher in clear cell RCC than other subtypes of Renal cell carcinoma (P<0.01). CONCLUSION: These data may justify the more routine use of this technique in the characterisation, assessment and follow–up of renal lesions especially small and indeterminate ones.