Volume : X, Issue : VI, June - 2020

ROLE OF DESMOPRESSIN IN NOCTURIA OF ADULTS

Dr. Ankush Gupta, Dr. Abhishek Yadav, Dr. Prashant Lavania

Abstract :

OBJECTIVE–To study the dose, effectiveness and the side effects of oral desmopressin in control or improvement of nocturia in adults more than 40 years old(40–80 years). METHOD– Out of the total 50 patients, two groups were divided of 25 patients each.25 patients received placebo while the other half received optimal dose of oral desmopressin after undergoing a dose titration phase which determined the optimal dose.All patients kept a 3–day frequency–volume charts (FVC). The efficacy assessments was based on data from the patients‘ FVC after the 4–week treatment period. The safety of oral desmopressin was evaluated based on the collected adverse events. RESULTS– Mean nocturnal void and mean nocturnal volume as per the FVC decreased in the patients treated with desmopressin.. CONCLUSION – Desmopressin was effective in nocturia with 0.2 mg being the most optimal dose and with the least side effects.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

ROLE OF DESMOPRESSIN IN NOCTURIA OF ADULTS, Dr. Ankush Gupta, Dr. Abhishek Yadav, Dr. Prashant Lavania INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020

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