Role of glutamine supplementation in wound healing post corn excision surgery

Dr. Tapas Bharat Arya; Dr. Juthikaa Deherkar; Dr. Pravin Borkar; Dr. R. S. Kharat

Volume : VIII, Issue : IV, April - 2018

Role of glutamine supplementation in wound healing post corn excision surgery

Dr. Tapas Bharat Arya, Dr. Juthikaa Deherkar, Dr. Pravin Borkar, Dr. R. S. Kharat

Abstract :

Introduction:Wound healing is a complex phenomena and is affected by numerous factors, nutritional deficiencies being on of them. Glutamine is required at every stage of wound healing. We aimed to study the role of glutamine supplementation in wound healing in patients who presented to our hospital for corn excision surgery.

Methodology: 80 patients who visited our hospital for corn excision surgery were randomly assigned to either the group receiving glutamine supplementation (Group G) or the control group receiving normal diet (Group C). Pre– and post–treatment comparisons were made between the two groups using the Bates Jensen wound assessment tool.

Results:Baseline characteristics and mean wound appearance and depth scores of the patients in the two groups were similar. However, after the treatment, mean wound appearance score was significantly higher in the glutamine group (4.39 ± 0.18) as compared to the control treatment (3.61 ± 0.34). Similarly, there was a significantly higher wound depth score in the glutamine group as compared to control group (p value <0.05). Post–treatment, wound constriction was 1.75 ± 0.01cm² and 1.63 ± 0.03 cm²in the glutamine and control group respectively (p value <0.05). Fiinolysis time was significantly lower in patients in the glutamine group (298.20 ± 112.20 minutes) as compared to the control group patients (332.72 ± 82.31 minutes).

Conclusions: The results of this study demonstrate that glutamine supports and accelerates the wound healing and decrease chances of infections. Further studies are required to identify the optimal dose and duration which will benefit patients in wound healing.