ROLE OF ORAL PROBIOTICS IN THE PREVENTION OF NECROTIZING ENTEROCOLITIS IN PRETERM NEONATES

Khalil Ahmad; Erum Yasmin; Shakeb Ahmad

Volume : X, Issue : VII, July - 2020

ROLE OF ORAL PROBIOTICS IN THE PREVENTION OF NECROTIZING ENTEROCOLITIS IN PRETERM NEONATES

Khalil Ahmad, Erum Yasmin, Shakeb Ahmad

Abstract :

Necrotizing enterocolitis (NEC) is the most commonly acquired intra–abdominal emergency and causes significant mortality and morbidity. A prospective randomized control trial was conducted in preterm neonate (<34 weeks of gestation) at in NICU of Jawaharlal Nehru Medical College Hospital, Bhagalpur, Bihar, India. The neonates in the test group were fed with Probiotics Darolac’ sachets with east milk twice daily till they reach full feeds. The neonates in the control group were fed with east milk alone.The incidence of NEC was significantly lower in the test group (3 of 100 vs. 10 of 100). The incidence of severe NEC was also significantly lower in the test group when compared with the control group (0 of 100 vs. 7 of 100). We conclude that Probiotics fed enterally with east milk reduced both the incidence and severity of NEC. However, the data are insufficient to comment on their short and long term safety.