Volume : X, Issue : V, May - 2020

Safety and efficacy of Fimasartan in patients with arterial hypertension compared with Telmisartan.

Dr Nirmal Garabadu, Dr Satya Narayan Routray

Abstract :

OBJECTIVE: Angiotensin receptor blockers (ARBs) are most widely prescribed antihypertensive drugs at present. This study was under taken to compare the efficacy and safety of the ninth ARB Fimarsartan with the most widely prescribed ARB Telmisartan. MATERIAL AND METHODS: Newly diagnosed stage 1 and 2 essential hypertension patients in the age group of 18 to 65 years of either sex were included in the study. Patients with hypersensitivity to ARBs, secondary hypertension, pregnant women, history of Drug/ Alcohol abuse, cardiac arrhythmias were excluded from the study. Patients who gave consent for the study were divided into 2 random groups 1 and 2 – the first received Fimasartan and the second received Telmisartan. Point of control was defined as blood pressure<140/90 mm of Hg. RESULTS: 120 patients were randomized into two groups. Out of 60 patients in group 1 who received Fimasartan, 3 lost for follow up. Out of 60 patients in group 2 who received Telmisartan, 4 lost for follow up. 75% patients in Fimasartan group and 78.33% in Telmisartan group had control of blood pressure. There was no significant difference between the two drugs in both mean systolic and diastolic blood pressure at 7 days, 1 month, 2 months and 6 months. Adverse effects encountered in 6% of the patients in Fimasartan group while it occurred in 5% of them in Telmisartan group. CONCLUSION: Fimasartan is an effective blood pressure lowering drug with efficacy and safety similar to that of Telmisartan.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

SAFETY AND EFFICACY OF FIMASARTAN IN PATIENTS WITH ARTERIAL HYPERTENSION COMPARED WITH TELMISARTAN., Dr Nirmal Garabadu, Dr Satya Narayan Routray INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-5 | May-2020

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