Screening of Aqueous Fruit Pericarp Extract of Cucumis Melo against Microorganisms Involved in Pathology of Various Diseases

Swathi P; Sravana Swathi V; Ramkishan A; Bhavani B

Volume : VII, Issue : VIII, August - 2017

Screening of Aqueous Fruit Pericarp Extract of Cucumis Melo against Microorganisms Involved in Pathology of Various Diseases

Swathi P, Sravana Swathi V, Ramkishan A, Bhavani B

Abstract :

The study aimed to evaluate the effect of aqueous pericarp extract of Cucumis melo (APCM) for antioxidant activity and anti microbial activities against human pathogenic organisms. The antioxidant activity of APCM was carried out to assess scavenging activity against superoxide, hydroxyl, hydrogen peroxide and DPPH radicals. The APCM showed significant antioxidant activity compared with ascorbic acid. The antimicrobial activity was tested against human pathogenic bacteria and fungi. The antimicrobial activity of APCM was studied by agar well diffusion method in vitro. The effect of antimicrobial potential was examined o both Gram positive and Gram negative pathogens like Salmonella typhi, Viio cholerae, Shigella dysenteriae, Enterococcus faecalis. The APCM has showed consistently significant inhibitory activity on different bacterial species tested and found the significance of antimicrobial activity. The present study revealed that the activities might be due to the presence of terpenoids and phenols in the pericarp of Cucumis melo.