Volume : X, Issue : VII, July - 2020

SEPTIC SHOCK AND ROLE OF LOW DOSE CORTICOSTEROIDS IN REFRACTORY SEPTIC SHOCK

Dr. Jyoti Jindal, Dr. Vikas Garg

Abstract :

OBJECTIVE: Whether low dose hydrocortisone therapy decreased the duration of vasopressor therapy and decrease the mortality in patients with refractory septic shock. METERIAL AND METHODS: A prospective observational study was conducted over a period of 15 months in tertiary care Hospital enrolling 104 patients as per the inclusion criteria They were started on Inj. Hydrocortisone 50 mg IV 6 hourly . RESULTS: Out of the total 104 patients 43.27% of patients have shown recovery as compared to 33.65% patients who expired. Survivors have significantly less time of shock reversal as compared to non–survivors (30 hours vs 80 hours) . APACHE–II score in survivors at 48 hr is 19.40+5.28 SD in comparison to non–survivors i.e.37.00+5.35 SD indicating APACHE – II score as an important predictor for outcome in severe sepsis. CONCLUSION: It was concluded that low dose hydrocortisone therapy decreased the duration of vasopressor therapy by decreasing the time of shock hours and it decreased the mortality in patients with refractory septic shock.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

SEPTIC SHOCK AND ROLE OF LOW DOSE CORTICOSTEROIDS IN REFRACTORY SEPTIC SHOCK, Dr. JYOTI JINDAL, Dr. VIKAS GARG INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-7 | July-2020

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