Volume : IV, Issue : XII, December - 2014
Serosurvey of Crimean Congo Haemorrhagic fever (CCHF) among high risk group during 2011 and 2013 CCHF outbreak in Gujarat, India
Gurav Yk, Yadav Pd, Deoshatwar Ar, Dhruwey Vs, Shete Am, Chaubal Gy, Tandale Bv, Raval Dk, Mourya Dt
Abstract :
Seroepidemiological study was conducted during the outeak of Crimean–Congo hemorrhagic fever (CCHF) in village Kolat (January– Feuary 2011) and village Karyana (July 2013) in Gujarat, India. Study was conducted to know the seroprevalence of CCHFV among at risk individuals which includes family contacts of CCHF case, household neighbourhood contacts, animal handlers and health care staff in the CCHF affected area. Detection of CCHF virus specific IgM and IgG antibodies were performed by using a commercial kit, Vector BEST Company. Sera from acute fever cases were screened for anti CCHFV IgM antibodies and for detection of CCHFV by Real Time RT–PCR. Anti–CCHFV IgG antibodies were not detected from village Kolat and 10 neighbouring villages of Kolat in January 2011 in Ahmedabad district. However, anti CCHFV IgG antibodies were detected in an animal handler from Ahemdabad. In year 2013, overall seroprevalence of 1.9% (5/261) was reported from Karyana village and 3.0% (1/33) from neighbouring Khambala village in Amreli District. This is the first serosurvey study in India performed in CCHF affected villages in Gujarat, which reported very low seropositivity of CCHF infection in the high–risk individual in the region, suggesting very low asymptomatic infection. The seroprevalence data in this study may be useful for public health to determine appropriate CCHFV interventions and preventive measures to be undertaken in the area where people are living in close proximity with the animals.
Keywords :
Crimean–Congo haemorrhagic Fever (CCHF) seroprevalence outbreak Infectious disease at risk population.
Article:
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DOI : 10.36106/ijar
Cite This Article:
Gurav YK,Yadav PD,Deoshatwar AR,Dhruwey VS,Shete AM,Chaubal GY,Tandale BV,Raval DK, Mourya DT Serosurvey of Crimean Congo Haemorrhagic fever
(CCHF) among high risk group during 2011 and 2013 CCHF outbreak in Gujarat, India Indian Journal of Applied Research, Vol.4, Issue : 12 December 2014
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Gurav YK,Yadav PD,Deoshatwar AR,Dhruwey VS,Shete AM,Chaubal GY,Tandale BV,Raval DK, Mourya DT Serosurvey of Crimean Congo Haemorrhagic fever (CCHF) among high risk group during 2011 and 2013 CCHF outbreak in Gujarat, India Indian Journal of Applied Research, Vol.4, Issue : 12 December 2014
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