Volume : VII, Issue : I, January - 2017

Serum IL1–beta and biochemical markers in myocardial infarction

Mrs. Smita Deokar, Dr. Sucheta Dandekar

Abstract :

 Objective–To assess serum interleukin–1β concentrations in patients with myocardial infarction and to examine whetherserum IL–1β concentrations correlatewith biochemical markers.

 

Design–  case–control study of patients with myocardial infarction.

 

Setting–  Intensive cardiac care unit of major municipal hospital.

 

Patients–patients withacute myocardialinfarction

 

Results–Mean(SD) serum IL–1β concentrationswere higher (P < 0.001) inpatients with MI (n =169; 2.85 (9.34) pg/ml),than in  169 healthy, age–matched controls 0.26 (1.25) pg/ml). Serum IL–1β concentrations had weak positive correlations with TG (r = 0.412, p <0.0005), cholesterol(r =0.196 p <0.0005), AST (r = 0.532, p <0.0005), ALT (r = 0.395, p <0.0005) and ALP (r = 0.314, p <0.0005)

 

Conclusion–Serum IL–1β concentrationsare raised in patients with myocardial infarction. The precise role of IL–lβ in coronaryartery disease is to be determined.

 

 

 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Mrs.Smita Deokar, Dr.Sucheta Dandekar, Serum IL1–beta and biochemical markers in myocardial infarction, Indian Journal of Applied Research,Volume : 7 | Issue : 1 | JANUARY 2017

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