Serum lactate and outcome in critically ill elderly admitted to ICU

Prof. Dr. Moatassem Salah Amer; Prof. Dr. Randa Reda Mabrouk; Prof. Dr. Tamer Mohamed Farid; Dr. Mohamed Shawky Khater; Dr. Rania Mohamed Abd elhamed Alakad; Mohamed Mortada Mohamed Goda

Volume : VI, Issue : V, May - 2016

Serum lactate and outcome in critically ill elderly admitted to ICU

Prof. Dr. Moatassem Salah Amer, Prof. Dr. Randa Reda Mabrouk, Prof. Dr. Tamer Mohamed Farid, Dr. Mohamed Shawky Khater, Dr. Rania Mohamed Abd Elhamed Alakad, Mohamed Mortada Mohamed Goda

Abstract :

 Background: elderly patients need for admission to ICU is increasing. With advancing age and associated comorbidities critically ill elderly patients have substantial mortality. The early recognition of patients at high risk of mortality is needed to plan care in advance and to control healthcare costs. Aim: To find out the relation between serum lactate and outcome in critically ill elderly admitted to ICU. Study design: A prospective study. Participants: Ninety elderly patients aged 60 years and above. Method: This study was performed in Geriatric ICU at Ain Shams University Hospitals including patients admitted for 24 hours or more. On admission each patient was subjected to clinical assessment including detailed medical history, in addition to laboratory investigations including serum lactate on admission, after six hours and lactate clearance was calculated, also APACHE II score was calculated. Results: The current study showed that the prevalence of hyperlactatemia on admission to ICU was 61 %, the rate of mortality among the study participants was 43%, and lactate clearance after six hours had higher sensitivity and specificity to predict ICU mortality in elderly than initial serum lactate on admission. Conclusions: In the current study we conclude that lactate clearance is the most important predictor of mortality in elderly admitted to ICU.