Serum Uric Acid Levels and Lipid profile in Preeclampsia Patients from Raigarh Chhattisgarh State

Dr. Harish Kumar Uraon; Priyanka Chandel

Volume : VI, Issue : XII, December - 2016

Serum Uric Acid Levels and Lipid profile in Preeclampsia Patients from Raigarh Chhattisgarh State

Dr. Harish Kumar Uraon, Priyanka Chandel

Abstract :

BACKGROUND: Hyperuricemia is one of the earliest and most consistent observations noted in preeclamptic pregnancies. It is a common cause of both maternal and perinatal morbidity and mortality in both developed and developing countries. AIMS & OBJECTIVES: To Study Serum Lipid profile & Uric Acid level in Hypertensive Disorders of Pregnancy. METHODS: A prospective case control study was conducted at Dept. of Biochemistry & Obstetrics and Gynecology of Late Shri Lakhiram Agrawal Memorial Medical College & Kirodimal Govt. hospital Raigarh Chhattisgarh. 30 cases of PE mothers and 30 normal healthy pregnant women served as control in this present study. Uric acid estimation was done by Uricase Peroxidase method while Lipid profile estimation was done by Cholesterol oxidase & Peroxidase method. SPSS version 16.0 was used for statistical analysis, student t–test and Pearson correlation were performed and p <0.05 is considered as statistically significant. RESULTS: The mean triglycerides (TG), total cholesterol (TC), LDL–cholesterol (LDL), VLDL (mg/dl), AST (IU/L), ALT (IU/L) ALP (IU/L), SBP and DBP levels were significantly higher in preeclampsia patients as compared to control. HDL–cholesterol (HDL), Urea (mg/dl) and Creatinine (mg/dl) were significantly lower in preeclampsia patients. CONCLUSION: The result showed that increase level of serum uric acid & lipid profile in PE pregnant women‘s. Increase level of serum uric acid & lipid profile are major role of pathogenesis & good marker for early diagnosis of PE Pregnant women