Severity, Preventability and Predisposing factors assessment of adverse cutaneous drug reaction: A prospective hospital based observational study.

Dr. Vimmi Agrawal; Dr. S. P. Pandey; Dr. Usha Gupta

Volume : V, Issue : VII, July - 2015

Severity, Preventability and Predisposing factors assessment of adverse cutaneous drug reaction: A prospective hospital based observational study.

Dr. Vimmi Agrawal, Dr. S. P. Pandey, Dr. Usha Gupta

Abstract :

Adverse cutaneous drug reactions (ACDR) are the commonly reported type of ADR. Cutaneous ADR patterns and the drugs causing various reactions are changing every year, which may be due to the emergence of newer molecules and changing trends in the use of drugs. Aims: Our objective was to assess severity, preventability and to identify any potential risk factor of reported ACDRs using suitable scales in the tertiary health care center. Methods: fifty five patients with adverse cutaneous drug reactions were recruited for this study during 2013–2014. Results: Assessing the severity of ACDRs is an essential component in Pharmacovigilance studies as an ACDR may require intervention. 87.27% patients had mild to moderate and 12.72% patients had severe ACDRs, 23.63% were considered definitely preventable & 52.72% patients had one or the other predisposing factors. polypharmacy was the most common predisposing factor observed in our study. Conclusion: implementing the ADRs reporting and monitoring system, one can promote drug safety and better patient care, among health care professionals.