Significance Of Thyroid Autoantibodies, Thyroid Function And ASST In Chronic Idiopathic Urticaria–––A Clinical Study

Dr. M.SubramanyaSwamy; Dr. Y.Arunakumari; Dr.I .Chandrasekhar Reddy; Dr.P. Amruthavalli; Dr.K.Murali Reddy

Volume : V, Issue : III, March - 2015

Significance Of Thyroid Autoantibodies, Thyroid Function And ASST In Chronic Idiopathic Urticaria–––A Clinical Study

Dr. M. Subramanyaswamy, Dr. Y. Arunakumari, Dr. I . Chandrasekhar Reddy, Dr. P. Amruthavalli, Dr. K. Murali Reddy

Abstract :

Background: Chronic urticaria comprises 25% among patients of urticaria. The prevalence of thyroid function alterations, and thyroid autoantibodies increasing in urticaria patients inspired us to undertake the present study. Materials and Methods: A total of 100 patients of chronic urticaria of 6 weeks duration attending to the department of dermatology during the period of 12 months were enrolled. Autologous serum skin test, Thyroid hormones,Thyroid autoantibodies were performed to all cases. Results: 3465 patients were presented with urticaria constitutes 12.1% of total number of patients attended during the period of 12 months. In this study group of 100 patients of chronic urticaria, ASST was positive in 46%, Thyroid autoantibodies was positive in 27%. Mean age of patients studied was 34.11 years. The mean duration of urticaria was 21.6 months and 13 months in TGA positive and TGA negative groups respectively. The significant female preponderance was observed (p>0.05). Abnormal thyroid function was seen in 8 patients. Conclusion: ASST,Thyroidprofile,and thyroid autoantibodies were considered to be screening tests for autoimmune urticaria. Thyroid dysfunction tests helps the patients who are likely to have more severe disease and require new modalities of treatment.