Spectral characterization, biological activities and DNA cleaving studies of 1–[(6–Methyl–pyridin–2–ylimino)–methyl]–naphthalen–2–ol and its metal(II) complexes

Thangavel Thamaraikannan; Akila Ekamparam; Rangappan Rajavel

Volume : VII, Issue : VIII, August - 2017

Spectral characterization, biological activities and DNA cleaving studies of 1–[(6–Methyl–pyridin–2–ylimino)–methyl]–naphthalen–2–ol and its metal(II) complexes

Thangavel Thamaraikannan, Akila Ekamparam, Rangappan Rajavel

Abstract :

Metal complexes derived from 2–hydroxy–naphthalene–1–carbaldehyde, 6–methyl–pyridin–2–ylamine and M(II) salts in ethanol solution are reported and characterized based on elemental analyses, IR, UV, molar conductance and magnetic moment. The complexes are found to have the formulae ML₂, where M= Co(II), Ni(II), and Cu(II) and L = 1–[(6–Methyl–pyridin–2–ylimino)–methyl]–naphthalen–2–ol. The molar conductance data reveal that the chelates are non–electrolytes. IR spectra show that the Schiff bases are coordinated to the metal ions in a tridentate manner with ONN donor sites. From the magnetic moment values, it is found that the geometrical structures of these complexes are octahedral. The synthesized ligand, in comparison to their metal complexes also were screened for their antibacterial activity against bacterial species, Bacillus subtilis, Staphylococcus aureus (as Gram–positive bacteria) and Klebsilla pneumonia and Escherichia coli (as Gram–negative bacteria). The activity data show that the metal complexes to be more potent/antibacterial than the parent organic ligands against one or more bacterial species