Spectrum of Haematological disorders on Bone Marrow Aspiration and Biopsy: A Retrospective Study of 498 cases

Dr Priya Bagale; Dr Meenal Shingade

Volume : VIII, Issue : XI, November - 2018

Spectrum of Haematological disorders on Bone Marrow Aspiration and Biopsy: A Retrospective Study of 498 cases

Dr Priya Bagale, Dr Meenal Shingade

Abstract :

Introduction: The present study was conducted in the department of pathology with the aim to evaluate the frequency of involvement of bone marrow in various haematological disorders and to assess utility of bone marrow examination to reach the final diagnosis.

Material methods: This was a retrospective study and total 498 bone marrow aspiration (BMA) and biopsies were included along with those cases where patient presented to us with hematological abnormalities. Clinical and laboratory data were retrieved from case files and laboratory records.

Results: BMA from 498 patients were analyzed. Megaloblastic anemia contributed highest number of cases among the non malignant haematological group. Acute myeloid leukemia was the commonest malignant haematological disorder. Among 498 cases, 256 were male and 242 were female patients with highest number of cases in the age group of 21–30 years.

Conclusion: Bone marrow examination plays important role not only in definitive tissue diagnosis, but also determine prognosis & further line of management in haematological and nonhematological disorders